Laboratory of Antibiotic Resistance & Virulence
School of Biological Sciences
National Institute of Science Education
and Research
“The joy of discovery is certainly the liveliest that the mind of man can ever feel” - - Claude Bernard
Journal Publications
2018
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Mishra M, Kumar S, Majhi RK, Goswami L, Goswami C, Mohapatra H. 2018. Antibacterial efficacy of polysaccharide capped silver nanoparticles is not compromised by AcrAB-TolC efflux pump. Frontiers in Microbiology (In press)
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Mohapatra DP, Singh SK, Sahoo M, Patole S, Mishra M, Debata NK and Mohapatra H. 2018. Retrospective study on clonal relationship of multidrug resistant Klebsiella spp. indicates closed circulation and initiation of clonal divergence. Journal of Medical Microbiology. DOI 10.1099/jmm.0.000715.
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2017
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Mishra M, Patole S, Mohapatra H. 2017. Draft genome sequences non-clinical and clinical Enterobacter cloacae isolates exhibiting multiple antibiotic resistance and virulence factors. Genome announcement. https://doi.org/10.1128/ genomeA.01218-17.
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Patole S, Mishra M, Mohapatra H. 2017. Draft genome sequences of clinical and non-clinical isolates of Klebsiella spp. exhibiting non-heritable tolerance towards antimicrobial compounds. Genome announcement. https://doi.org/10.1128/genomeA.01217-17.
Santosh Kumar Singh, Mitali Mishra, Minu Sahoo, Shashank Patole, Suneeta Sahu, Sudhi Ranjan Mishra and Harapriya Mohapatra. 2017. Antibiotic resistance determinants and clonal relationships among multidrug-resistant isolates of Klebsiella pneumoniae. Microbial Pathogenesis. 110: 31-36
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Singh SK, Ekka R, Mishra M, Mohapatra H. 2017. Association study of Multiple Antibiotic Resistance and Virulence: A strategy to assess extent of risk posed by bacterial population in aquatic environment, Environmental Monitoring and Assessment. 189: 320.
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Singh SK, Mishra M, Sahoo M, Patole S, Mohapatra H. 2017. Efflux mediated colistin resistance in diverse clones of Klebsiella pneumoniae from aquatic environment. Microbial Pathogenesis. 102:109-112.
2016
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Sanyasi S, Majhi RK, Kumar S, Mishra M, Ghosh A, Suar M, Satyam PV, Mohapatra H, Goswami C, Goswami L. 2016. Polysaccharide-capped silver Nanoparticles inhibit biofilm formation and eliminate multi-drug-resistant bacteria by disrupting bacterial cytoskeleton with reduced cytotoxicity towards mammalian cells. Scientific Reports. 29; 6:24929. doi: 10.1038/srep24929.
Upto 2010
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Saswat S. Mohapatra, Chinmay K. Mantri, Harapriya Mohapatra, Rita R. Colwell, and Durg V. Singh (2010). Analysis of clonally related environmental Vibrio cholerae O1 El Tor isolated before 1992 from Varanasi, India reveals origin of SXT-ICEs belonging to O139 and O1 serogroups. Environmental Microbiology Reports, Environmental Microbiology Reports, 2(1), 50–57.
Harapriya Mohapatra, Saswat S. Mohapatra, Chinmay K. Mantri, Rita Colwell and Durg V. Singh (2008). Vibrio cholerae non-O1, non-O139 strains isolated before 1992 from Varanasi, India are multiple drug resistant, contain intSXT, dfr18 and aadA5 genes. Environmental Microbiology, 10(4): 866-873.
Durg V. Singh and Harapriya Mohapatra (2008). Application of DNA based methods in typing Vibrio cholerae strains. Future Microbiology, 3 (1): 87 – 96.
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Harapriya Mohapatra and Rani Gupta (2005). Concurrent sorption of Zn(II), Cu(II) and Co(II) by Oscillatoria angustissima as a function of pH in binary and ternary metal solutions. Bioresource Technology, 96 (12): 1387 – 1398.
Rani Gupta, Paresh Gigras, Harapriya Mohapatra, Vineet Kumar Goswami and Bhavna Chauhan (2003). Microbial α-amylases: a biotechnological perspective. Process Biochemistry, 38 (11): 1599 - 1616.
Rani Gupta and Harapriya Mohapatra (2003). Microbial biomass: An economical alternative for removal of heavy metals from waste water. Indian Journal of Experimental Biology, 41 (9): 945-966.
Prerna Ahuja, Harapriya Mohapatra, R. K. Saxena and Rani Gupta (2001). Reduced uptake as a mechanism of zinc resistance in Oscillatoria angustissima. Current Microbiology, 43 (5): 305 – 310.
Rani Gupta, Prerna Ahuja, Seema Khan, R. K. Saxena and Harapriya Mohapatra (2000). Microbial biosorbents: Meeting challenges of heavy metal pollution in aqueous solutions. Current Science, 78 (8): 967 – 973.
Book chapters
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Harapriya Mohapatra, Saswat S. Mohapatra, Chinmay K. Mantri and Durg V. Singh: Horizontal gene transfer and ICEs: a perspective with reference to SXT ICEs in Vibrio cholerae. In New Horizons in Biotechnology, Asiatech Publishers Inc., Delhi. pp 388-403.
Rani Gupta, R. K. Saxena, Harapriya Mohapatra and Prerna Ahuja (2002). Microbial variables for bioremediation of heavy metals from industrial effleunts. In V. P. Singh and R. D. Stapleton (Eds.) Biotransformations: Bioremediation Technology for Health and Environmental Protection, Progress in Industrial Microbiology Vol. – 36, Elsevier Science Publishers, Amsterdam, Netherlands, pp. 189 – 230.
Rani Gupta, Harapriya Mohapatra and R. K. Saxena (2000). Chitinases and their Potential Application: Present status and Future prospects. In K. G. Mukerji, B. P. Chamola and A. K. Sharam (Eds.) Glipmses in Botany, APH Publishing Corporation, New Delhi, pp. 223 – 238.
Rani Gupta, Harapriya Mohapatra and R. K. Saxena (2001). Soil Microflora :Isolation, enumeration and identification. In K. G. Mukerji (ed.) Techniques in Mycorrhizal Research, Kluwer Academic Publishers, Dordrecht, Netherlands.
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Conference presentations
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Roseleen Ekka, Santosh Kumar Singh and Harapriya Mohapatra. 2011. Prevalence and diversity of antibiotic resistance in bacterial isolates from aqueous environment. 1st Global Forum on Bacterial Infections: Balancing Treatment Access and Antibiotic Resistance, New Delhi.
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Harapriya Mohapatra, Santosh Singh and Mitali Mishra. 2012. Overcoming the antibiotic hurdle: resistance versus tolerance’, SBCI, Mini symposium, NISER, Bhubaneswar
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"Diversity and function of multidrug efflux pumps in Enterobacter sp." Mitali Mishra, Santosh Kumar Singh, Harapriya Mohapatra, 53rd Annual Conference of Association of Microbiologist of India, 22nd to 25th November 2012, KIIT University, Bhubaneswar.
"Factors affecting non-genetic tolerance towards antimicrobial agents in Klebsiella pneumoniae”. Santosh Kumar Singh, Mitali Mishra, Harapriya Mohapatra, 53rd Annual Conference of Association of Microbiologist of India, 22nd to 25th November 2012, KIIT University, Bhubaneswar.
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Response of multidrug efflux pump to physiological stimuli in Enterobacter spp.” Mitali Mishra, Suneeta Sahu, Harapriya Mohapatra. XXXVIII All India Cell Biology Conference and International Symposium on ‘Cellular Response to Drugs, 10 – 12th December 2014, Central Drug Research Institute, Lucknow, India
Antibiotic resistance profile and molecular basis of drug resistance in clinical Klebsiella pneumoniae isolates from Odisha”, Santosh Kumar Singh1, Suneeta Sahu2, Sudhi Ranjan Mishra2 and Harapriya Mohapatra. International Conference on “Antimicrobial resistance, Novel Drug Discovery and Development: Challenges and Opportunities”, SRM University Haryana, Sonepat and in association with International Association of Medical & Pharmaceutical Virologists (IAMPV), March 2-3, 2015, India Habitat Centre, Lodhi Road, New Delhi-110003.
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A study on pH dependent modulation of carbonyl cyanide m-chlorophenylhydrazone (CCCP) activity and efflux pump functioning in Enterobacter isolates”. Mitali Mishra, Debiprasad Mohapatra, Nagen Kumar Debata, Harapriya Mohapatra”, Gordon Research Conference on Multidrug Efflux Systems, from 04/25/2015 to 05/01/2015, at Renaissance Tuscany Il Ciocco in Lucca (Barga) Italy
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“Studies on acrAB-tolCmulti drug efflux pump expression in response to pH and antibiotic stress in Enterobacter isolates”, Mitali Mishra, DebiprasadMohapatra, Nagen Kumar Debata, Harapriya Mohapatra”, Gordon Research Conference on Multidrug Efflux Systems, Gordon Research Conference on Multidrug Efflux Systems, from 04/25/2015 to 05/01/2015, at Renaissance Tuscany Il Ciocco in Lucca (Barga) Italy
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Presented poster and abstract entitled “Antibiotics resistance profile and molecular basis of drug resistance in clinical isolates of Klebsiella pneumoniae from Odisha” in International Conference on Antimicrobial Resistance, Novel Drug Discovery and Development: Challenges and Opportunities held at New Delhi, from March 2-3, 2015.
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Study on persister cell formation in Klebsiella pneumoniae. Shashank Patole, Debi Prasad Mohapatra, Nagen K Debata, Harapriya Mohapatra. EMBO-FEMS Lecture Course - The New Microbiology, Spetses, Greece, 24th Aug-1st Sept. 2016.
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Mitali Mishra and Harapriya Mohapatra. “Outer membrane proteins of Enterobacter spp: Association with antibiotic resistance and virulence factors”; International Union of Microbiological Societies (IUMS), 17-21 July 2017, Singapore